Bronchiolitis Obliterans after Allogenic Bone Marrow Transplantation: HRCT Findings

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Bronchiolitis Obliterans after Allogenic Bone Marrow Transplantation: HRCT Findings

OBJECTIVE To evaluate the high resolution computed tomography (HRCT) findings of bronchiolitis obliterans (BO) after bone marrow transplantation (BMT). MATERIALS AND METHODS During the past three years, 11 patients were diagnosed as having BO after BMT when they developed irreversible air flow obstruction, with an FEV(1) value of less than 80% of the baseline value, without any clinical evide...

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Bronchiolitis obliterans complicating bone marrow transplantation.

A 19-year-old woman with extensive, persistent chronic graft versus host disease (GVHD), following an HLA-identical bone marrow graft for acute leukemia, developed rapidly progressive airflow obstruction 140 days post-transplantation (PT) and presented clinically with persistent cough, inspiratory rales, bronchospasm and exertional dyspnea. Pulmonary function tests (PFT) showed rapidly evolving...

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Chest computed tomography in bronchiolitis obliterans after bone marrow transplantation

Radiol Bras. 2017 Mai/Jun;50(3):IX Bronchiolitis obliterans (BO) is an inflammatory disease of the small airways, resulting from damage to the lower respiratory tract. The presence of inflammation and fibrosis of the terminal and respiratory bronchioles results in narrowing or complete obliteration of the airway lumen, leading to chronic airflow obstruction. Histologically, BO is characterized ...

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ALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA

Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...

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[Allogenic bone marrow transplantation].

Allogeneic bone marrow transplantation (BMT) after high-dose, marrow-ablative chemoradiotherapy has been established as the treatment of choice for various hematologic, neoplastic, and congenital disorders. The most common type of marrow graft is an allogeneic one from a sibling donor who has compatible human leukocyte antigen (HLA). Only 30% of patients requiring allogeneic BMT have an HLA-com...

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ژورنال

عنوان ژورنال: Korean Journal of Radiology

سال: 2004

ISSN: 1229-6929

DOI: 10.3348/kjr.2004.5.2.107